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Study Shows Sutures Produce Fewer Complications Than Staples After C-Sections

A prospective study found that the use of sutures to close the skin after a caesarean delivery results in fewer wound complications than the use of staples, Reuters reports. Suzanne Basha and colleagues at the Lehigh Valley Health Network in Pennsylvania led a prospective trial of 416 women giving birth via c-section who were randomly [...]

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Osteopontin Contributes To Allergic Contact Dermatitis

Dr. Johannes M. Weiss and colleagues at the University of Ulm, Ulm, Germany have discovered that osteopontin (OPN) contributes to allergic contact dermatitis. They present these findings in the January 2010 issue of the American Journal of Pathology…

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Burns Patients Awaiting Skin Grafts: Human Embryonic Stem-Cells Could Be Used To Generate Temporary Skin

A study in this week’s edition of The Lancet reports that the use of human embryonic stem-cells (hESCs) is a promising alternative for producing temporary skin substitutes for patients awaiting skin grafts after, for example, serious burn injuries. The article is the work of Dr Christine Baldeschi, INSERM and Institute for Stem Cell Therapy and [...]

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New Study Ushers In Spring-Time For Slow Inactivation

The December 2009 issue of the Journal of General Physiology (JGP) contains a paper by Christopher Ahern (The University of British Columbia, Vancouver) and colleagues that explores pore mutation effects in Shaker and other K+ channels using in vivo nonsense suppression technology. The study was published online November 16 (http://www.jgp.org).

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Link Between Light Touch And Merkel Cells Solves 100-year Mystery

Light touch – the sense that lets musicians find the right notes on a keyboard, a seamstress revel in the feel of cool silk, the artisan feel a curve in material and the blind read Braille – truly depends on the activity of Merkel cells usually found in crescent-shaped clusters in the skin, said researchers [...]

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Editorial: Physicians Must Help Men Overcome Barriers To Care

“A growing body of sex-specific studies shows a trend among men, especially white middle-class men, of delaying seeking help when they become ill,” writes June K. Robinson, M.D., of Northwestern University Feinberg School of Medicine, Chicago, and editor of Archives of Dermatology, and colleagues in an accompanying editorial. “By delaying seeking care, men present at [...]

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Avotermin Could Give Accelerated And Permanent Improvement In Scarring

The drug avotermin (Juvista) could provide accelerated and permanent improvement in scarring following injuries. The findings are reported in an Article in this week’s Lancet, written by Professor Mark Ferguson, University of Manchester, UK, and Renovo, Manchester, UK, and colleagues. Skin is the most frequently injured tissue, and millions of people worldwide [...]

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Organotypic Cultures Help To Unravel How A Transcription Factor Modulates Crosstalk Between Different Layers Of The Skin

Mammalian skin requires constant maintenance, but how do skin cells know when to proliferate and at what rate? In the March 23, 2009 issue of the Journal of Cell Biology, Nguan Soon Tan and colleagues reveal that skin fibroblasts use a protein called PPARβ/δ to make sure overlying epithelial cells don’t proliferate too quickly. Their [...]

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Research Yields Potential Target For Cancer, Wound Healing And Fibrosis

Research conducted by Allison Berrier, PhD, Assistant Professor of Oral and Craniofacial Biology at the LSU Health Sciences Center New Orleans School of Dentistry, and colleagues, provides insights that may help scientists design novel approaches to control wound healing and fight diseases such as cancer and fibrosis.

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Hair Samples Can Be Used To Measure Effectiveness Of Antiretrovirals, Researchers Say

Hair strands might help determine the effectiveness of antiretroviral drugs for HIV-positive people, researchers from the University of California-San Francisco said recently, VOA News reports. Monica Gandhi of the university and colleagues have found that antiretroviral levels in hair samples strongly correlate with HIV levels in patients.

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